PUBLICATION

New

Chemical Proteomics Reveals

New Targets of Cysteine

Sulfinic Acid Reductase

Nat Chem Biol 2018

Our Commitment to Diversity

My lab welcomes students, postdocs and visiting scholars regardless race, religion, gender identification, sexual orientation, age, or disability status. The more reflective of society’s diversity the lab is, the better we are. It is through diverse perspectives and abilities that we see all possible answers to a problem.

Diverse Redoxome Reactivity Profiles of Carbon Nucleophiles

Gupta, V.; Yang, J.; Liebler, D.; Carroll, K. S. J. Am. Chem. Soc. 2017, DOI: 10.1021/jacs.7b01791

Functional site discovery in a sulphur metabolism enzyme using directed evolution

Paritala, H.; Palde, P. B.; Carroll, K. S. ChemBioChem 2016, 17(19): 1873-8, PMID27411165.

Molecular basis for redox activation of epidermal growth factor receptor kinase

Truong, T. H.; Ung, P. M.; Paulsen, C. E.; Prakash, P. B.; Schlessinger, A.; Carroll, K. S. Cell Chem. Biol. 2016, 23(7): 837-48, PMC4958504.

An immunochemical approach to detect oxidized protein tyrosine phosphatases using a selective C-nucleophile tag

Garcia, F. J.; Carroll, K. S. Mol. Biosystems 2016, 12(6): 1790-8, PMC4879066.

Reactivity, selectivity, and stability in sulfenic acid detection: A comparative study of nucleophilic and electrophilic probes

Gupta, V.; Carroll, K. S. Bioconj. Chem. 2016, 27(5): 1411-8, PMC4886738.

Rational design of reversible and irreversible cysteine sulfenic acid-targeted linear C-nucleophiles

Gupta, V.; Carroll, K. S. Chem. Comm. 2016, 52(16): 3414-7, PMC4830130.

First-in-class inhibitors of sulfur metabolism with bactericidal activity against non-replicating M. tuberculosis

Palde, P. B.; Bhaskar, A.; Pedró Rosa, L. E.; Madoux, F.; Chase, P. Gupta, V.; Spicer, T.; Scampavia, L.; Singh, A.; Carroll, K. S. ACS Chem. Biol. 2016, 11(1): 172-84, PMC4729198. *Highlighted in Nat. Chem. Biol. 2016.*

Profiling the reactivity of cyclic C-nucleophiles towards electrophilic sulfur in cysteine sulfenic acid

Gupta, V.; Carroll, K. S. Chem. Sci. 2016, 7(1): 400-15, PMC4724439.

The expanding landscape of the thiol redox proteome

Yang. J.; Carroll, K. S.; Liebler, D. C. Mol. Cell Proteomics 2016, 15(1): 1-11, PMC4762510.

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Our Latest Publications

News

Congrats, Kate

June 26, 2017

Lab PI, Kate Carroll's renewal R01 application entitled, "Probing the role of cysteine sulfenylation in cell signaling" was officially funded.

Welcome, Youai

June 14, 2017

The lab welcomes Youai, a new research technician. She completed her PhD from the University of Waterloo. Youai brings significant expertise in microbiology and cell biology.

Welcome, Roberta

June 5, 2017

The lab welcomes Roberta Farina, a new postdoctoral research associate. She completed her PhD from the University of Bari with Professor Angelo Carotti. Roberta brings significant expertise in synthetic organic chemistry and medicinal chemistry....

Welcome, Renan

May 24, 2017

The lab welcomes Renan Barroso Ferreira, a new postdoctoral research associate. He completed his PhD at the University of Florida, Gainsville with Professor Ron Castellano. Renan brings significant expertise in synthetic organic chemistry and the medicinal chemistry of...

Welcome, Yunlong

April 24, 2017

The lab welcomes Yunlong Shi, a new postdoctoral research associate. He completed his PhD from NC State University with Professor Josh Pierce. Yunlong brings significant expertise in synthetic organic chemistry, natural products and chemical biology....

Press, C&E News

April 24, 2017

Our recent JACS article, "Diverse Redoxome Reactivity Profiles of Carbon Nucleophiles" was highlighted in C&E News. See here.

Publication, JACS

April 10, 2017

Congratulations to first author, Vinayak Gupta on the publication of our manuscript, "Diverse Redoxome Reactivity Profiles of Carbon Nucleophiles" in the Journal of the American Chemical Society.

Congrats, Prakash

April 6, 2017

Postdoctoral Research Associate, Prakash Palde has accepted the position of Principle Scientist in the Biophysics Group of the Pfizer Oncology Research Unit in San Diego, California.

Congrats, Thu

March 20, 2017

Carroll lab graduate student alumn, Thu Truong, was the recipient of an NIH individual postdoctoral fellowship (F32). Her postdoctoral grant proposals to ACS and Susan G. Komen were also funded.

Congrats, Candice

March 6, 2017

Carroll lab graduate student alumn, Candice Paulsen, has accepted a tenure-track Assistant Professor position in the Department of Cellular and Molecular Physiology at Yale University.

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Upcoming Events

Russian Redox Meeting

7/17-7/23

ACS Washington, D.C.

8/21 - 8/25

Sulfur Conference

Hungary

9/9 - 9/15

Hello, We're the Carroll Lab

Kate S. Carroll

Principle Investigator

Christina Dreyton

Research Associate

Roberta Farina

Research Associate

PUBLICATION

New

Our Commitment to Diversity

Our Latest Publications

News

Congrats, Kate

Welcome, Youai

Welcome, Roberta

Welcome, Renan

Welcome, Yunlong

Press, C&E News

Publication, JACS

Congrats, Prakash

Congrats, Thu

Congrats, Candice

Upcoming Events

Russian Redox Meeting

7/17-7/23

ACS Washington, D.C.

8/21 - 8/25

Sulfur Conference

Hungary

9/9 - 9/15

Hello, We're the Carroll Lab

Kate S. Carroll

Principle Investigator

Christina Dreyton

Research Associate

Roberta Farina

Research Associate

Youngeun Jung

Research Associate

Yunlong Shi

Research Associate

Youai Hao

Research Technician

Salma Akter

Research Associate

Renan Ferreira

Research Associate

Darren Turner

Undergraduate